Its structure was established through analysis using nuclear magnetic resonance at Tohoku University, Harvard University and the University of Tokyoin combination w… Department of Chemistry, School of Science, The University of Tokyo Hongo, Bunkyo‐ku, Tokyo 113 (Japan) Fax: Int. code +(3)5800‐6898 e‐mail: ktachi@chem.s.u‐tokyo.ac.jp,Faculty of AGriculture, Tohoku University (Japan).This work was supported in part by a Grant‐in‐Aid from the Ministry of Education, Science and Culture, Japan.Use the link below to share a full-text version of this article with your friends and colleagues.Please check your email for instructions on resetting your password. It resembles large fatty acid chains and it is notable because it is one of the largest and most complex non-protein, non-polysaccharide molecules produced by any organism. [Na+],Except where otherwise noted, data are given for materials in their,CS1 maint: multiple names: authors list (,"Contraction and increase in tissue calcium content induced by maitotoxin, the most potent known marine toxin, in intestinal smooth muscle","Maitotoxin converts the plasmalemmal Ca2+ pump into a Ca2+-permeable nonselective cation channel","Maitotoxin-induced membrane blebbing and cell death in bovine aortic endothelial cells","Synthesis of the ABCDEFG Ring System of Maitotoxin","Synthesis and Biological Evaluation of QRSTUVWXYZA′ Domains of Maitotoxin",http://www.rsc.org/chemistryworld/2015/01/chemistry-grandest-total-synthesis-challenge-maitotoxin-put-hold-lack-funds,4-Aminopyridine (fampridine/dalfampridine),Transient receptor potential channel modulators,https://en.wikipedia.org/w/index.php?title=Maitotoxin&oldid=977011642,Pages using collapsible list with both background and text-align in titlestyle,Articles containing unverified chemical infoboxes,Wikipedia articles in need of updating from February 2017,All Wikipedia articles in need of updating,Creative Commons Attribution-ShareAlike License. and you may need to create a new Wiley Online Library account.Enter your email address below and we will send you your username,If the address matches an existing account you will receive an email with instructions to retrieve your username,I have read and accept the Wiley Online Library Terms and Conditions of Use.Number of times cited according to CrossRef:Methods for determining the absolute configurations of marine ladder‐shaped polyethers.Structure-Activity Relationship Studies of Maitotoxin Based on Chemical Synthesis.Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules.Natural Products as a Foundation for Drug Discovery.Total Synthesis, Stereochemical Revision, and Biological Assessment of Iriomoteolide‐2a.Total Synthesis of a Marine Macrolide Natural Product, Iriomoteolide-2a: The Fundamental Role of Total Synthesis in Natural Product Chemistry海洋マクロリド天然物iriomoteolide-2aの全合成：複雑な天然物の構造決定と生物活性評価における全合成の役割.Journal of Synthetic Organic Chemistry, Japan.Syntheses and Biological Activities of the LMNO, -LMNO, and NOPQR(S) Ring Systems of Maitotoxin Between 2007 and 2011, KC’s team completed three more maitotoxin fragments, the largest containing nine rings. .Maitotoxin-4, a Novel MTX Analog Produced by Gambierdiscus excentricus.Stereodivergent Synthesis and Configurational Assignment of the C1–C15 Segment of Amphirionin-5.Chemical Diversity, Origin, and Analysis of Phycotoxins.Synthetic Studies on Amphirionin-5: Stereochemical Assignment/Reassignment of the C1–C9 Portion through Stereodivergent Synthesis.Hb25_Springer Handbook of Marine Biotechnology.Total Synthesis and Complete Structural Assignment of Gambieric Acid A, a Large Polycyclic Ether Marine Natural Product.Synthesis and Biological Activity of the C′D′E′F′ Ring System of Maitotoxin.Synthesis and Biological Activity of the QRS Ring System of Maitotoxin.Polyketide biosynthesis in dinoflagellates: what makes it different?.Current Understanding and Hypotheses on the Biosynthesis of Microalgal Polyether Toxins.Toxins and Biologically Active Compounds from Microalgae, Volume 1.Synthesis and Biological Evaluation of QRSTUVWXYZA′ Domains of Maitotoxin.Journal of the American Chemical Society.Total Synthesis of Marine Polycyclic Ether Natural Products.An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis.The Psymberin Story—Biological Properties and Approaches towards Total and Analogue Syntheses.Psymberin – biologische Eigenschaften und Ansätze zu Total‐ und Analogasynthesen.The Failure of Epoxide Ring Opening and the Limits of Cascade Reactions.Artificial ladder-shaped polyethers that inhibit maitotoxin-induced Ca2+ influx in rat glioma C6 cells.Bioorganic & Medicinal Chemistry Letters.Diastereoselective Reductive Ring Expansion of Spiroketal Dihydropyranones to
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